BDBM50380140 CHEMBL2011155::carbonic anhydrase (CA) inhibitors, benzenesulphonamide ligand, 10
SMILES NS(=O)(=O)c1cc(ccc1Cl)C(=O)CSc1ncccn1
InChI Key InChIKey=ZHRHWGNFAKOKSF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50380140
Affinity DataKoff: 8.80E+5s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as association rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKon: 0.160M-1s-1Assay Description:Binding affinity to human recombinant CA12 catalytic domain assessed as dissociation rate constant after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 180nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain after 30 secs by surface plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKd: 500nMAssay Description:Binding affinity to human recombinant CA12 catalytic domain by fluorescence-based thermal shift assayMore data for this Ligand-Target Pair
Affinity DataKon: 1.60M-1s-1Assay Description:Binding affinity to CA12 (unknown origin) assessed as dissociation rate constant at pH 7 by SPR assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.80nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptors in rat striatal membranesMore data for this Ligand-Target Pair
Affinity DataKd: 1.67E+3nMAssay Description:Binding affinity to human recombinant carbonic anhydrase 12 by thermal shift assayMore data for this Ligand-Target Pair